Instrumentation

X-ray scattering. We use a fixed-anode mirror system to do small and large-angle x-ray scattering on to reveal order in and structure of lipids, proteins, and DNA. An example of scattering off of oriented DNA samples is shown above. Images by Luka Curovic.
X-ray scattering. We use a fixed-anode mirror system to do small and large-angle x-ray scattering on to reveal order in and structure of lipids, proteins, and DNA. An example of scattering off of oriented DNA samples is shown above. Images by Luka Curovic.

Physicists often develop new techniques that are adapted by biologists and the medical community for use in measurement and imaging.  From x-rays to the CT scan, innovations in physical measurement often drive new discovery and provide powerful diagnostics. Our capabilities include:

  • Single-molecule-sensitive fluorescence
  • Single-molecular-pair fluorescence resonance energy transfer (spFRET) with or without alternating laser excitation (ALEX)
  • Fluorescence Correlation Spectroscopy
  • Dynamic light scattering and electrophoretic mobility measurements
  • Scanning confocal microscopy
  • Superresolution microscopy
  • Particle tracking
  • Fluorescence lifetime measurements
  • Single channel measurements.
  • Droplet-confined single-molecule measurements.