Molecular Biophysics

Inside a virus, the pressure felt by the DNA can be as high as 80 atmospheres. For comparison, a champagne bottle is 5 atmospheres.  How does DNA order under these conditions?  Based on experimental determinations, these are graphical renditions of DNA arrays at high and intermediate densities.  Images and work attributed to Adrian Parsegian and Rudlolf Podgornik.
Inside a virus, the pressure felt by the DNA can be as high as 80 atmospheres. For comparison, a champagne bottle is 5 atmospheres. How does DNA order under these conditions? Based on experimental determinations, these are graphical renditions of DNA arrays at high and intermediate densities. Images and work attributed to Adrian Parsegian and Rudlolf Podgornik.

Molecular biophysics is the study of biological macromolecules such as DNA, RNA, proteins, and structural polysaccharides. Physical methods including x-ray, neutron, and light scattering, fluorescence, and NMR are to elucidate structure, operational dynamics, and conformational transitions of these molecules. These structures and structural changes are then related to biological function.