The CBP consists of faculty, research staff, visitors, and students at UMass Amherst. It has collaborators across campus and in the Five College region of Western Massachusetts. Affiliated faculty serve on the Executive Committee and the Steering Committee. The director of the CBP is Adrian Parsegian.
Department of Physics and Astronomy, Amherst College
Folding of DNA during spermatogenesis using particle tracking and optical tweezers; particle tracking inside of the cell to study cytoskeleton formation.
Folding, assembly, dynamics and functional mechanism of pore-forming membrane proteins, and their applications in biotechnology.
Department of Food Science
Luminescence Spectroscopy, Physical properties, Non linear Kinetics, Biophysics of Digestion, Predictive Microbiology, Food Security.
Professor and CBP Executive Board Member
The role of membrane tension, morphology, and composition in guiding the binding and activity of proteins relevant to cell trafficking and communication.
School of Natural Science, Hampshire College
Electron cryotomography of protein machines in cells and HIV from a biological and social context.
Inter-macroionic association and phase separation in polyelectrolyte, protein and surfactant systems.
Research Associate Professor
Department of Biochemistry & Molecular Biology
Protein folding from simulations to test tubes to cells, and how peripheral membrane enzymes recognize and search cell membranes.
Departments of Biochemistry & Molecular Biology and Chemistry
Protein folding in the cell and molecular mechanisms of Hsp70 chaperones.
Professor and CBP Director
Single-molecule-sensitive biophysics with an emphasis on molecular mechanics and interactions in confining and complex environments.
Biochemistry and Molecular Biology
The study of protein structure, protein-membrane and protein-protein interactions using a variety of biophysical, biochemical, and molecular biological approaches.
Assistant Professor and CBP Executive Board Member
Mechanical aspects of the cell, including spindle dynamics and microrheology of in vitro reconstituted actin-microtubule networks.
Expanding our understanding of hearing and measuring the biophysical properties of hair cells using electrophysiological tools and imaging techniques.
Professor of Polymer Science and Engineering
Polymer Science and Engineering Department
Understanding how macromolecules, both biological and synthetic, assume their sizes and shapes, organize into assemblies, and move around in crowded environments.
Professor Emeritus and Past CBP Director
Theory and measurement of intermolecular forces organizing soft matter.
Chemical Engineering Department
Utilizing self-assembly, molecular design, and microfluidic technologies to generate biomimetic microenvironments that enable the study and implementation of biomolecules to address real-world challenges.
Department of Chemical Engineering
Cancer metastasis, cell biomechanics and bioengineering.
Theoretical investigations of biological macromolecules and assemblies.
Associate Professor and CBP Executive Board Member
Microtubule Biophysics: Intracellular organization and non-equilibrium physics.
To understand, on a molecular level, how the small protein ubiquitin controls the dynamics of biochemical pathways to maintain normal cellular function.
Mechanical and Industrial Engineering
Biophysical regulation of stem cell fate, developmental biomechanics, mechanotransduction, BioMEMS, and tissue engineering.
Mechanisms of transmembrane signaling and transport by membrane proteins, including bacterial chemotaxis receptors and ABC transporters.
Electronic transport through bacterial pili and biofilms, and microbial fuel cells.
Assembly of the mammalian mitotic spindle. Current projects examine regulation of mitotic motor proteins by the microtubule associated protein, TPX2, using live cells and in vitro TIRF assays.